In this modern world with modern technologies and techniques, life
has been modified to a greater extent. The advance technologies, greater
medical facilities and inventions of new methods of treatment
contribute a lot in medical field and improving the life quality of the
individuals but still the power of life is defeated by the fatal or
lethal diseases. Human body is capable of doing extremely extraordinary
functions but these functions become workless in front of these lethal
biological armaments. With the improvement in quality of life, the
quantity of life shows no guarantee when there is matter of these deadly
diseases. With advance technologies and innovative researches many
treatment aims are introduced but the deadly nature of these diseases is
a bitter truth of life. Here is the list of top 10 most lethal diseases in the world.
This list will definitely resolve the conflicting question in minds
that what are the top most lethal diseases and what are the factors that
make them to be in this list. Know about their causes and sign symptoms
and do preventive measurements as Prevention is better than Cure and
also about their complications that make them more deadly.
10. Pneumonia
The most common lethal nosocomial infectious disease is Pneumonia. It
is an inflammatory disease of the lungs and can be life threatening. It
is more serious for older people above than 65, infants and children
and the individuals with other health issues. Its common symptoms
include fever, cough, chest pain and difficult in breathing. The treatment
is according to underlying cause like pneumonia caused by bacteria is
treated with antibiotics. It affects around 450 million individual each
year worldwide and therefore resulting in 4 million deaths mostly in
third world countries. William Osler titled pneumonia as “the captain of
the men of death” in the 19th century but the advancement in medical
field in the 20th century by advent of vaccines and antibiotic therapy
the improvement has been seen. It is one of the principal causes of
death in children under 5 years of age in all over the world.
9. Tuberculosis
Tuberculosis also known as TB or white plaque is a common infectious
disease, that is lethal in many cases and is caused by mycobacterium
tuberculosis. It is a contagious disease and is spread by sneezing,
coughing and talking. It usually affects the lungs of the sufferer but
can also affect the other parts of the body. If left untreated this
disease kills more than 50% of the infected individuals. The typical
symptoms of this disease include chronic cough, fever, blood with
sputum, weight loss and night sweats. Its treatment is complicated that
include administration of multiple antibiotics for a long duration of
time. The prevention of this disease is confined to screening programs
and proper vaccination. In 2010, according to estimation in developing
countries there were 8.8 million new cases of this disease and 1.5
million deaths because of it. After HIV, it is the second leading cause
of death from infectious diseases.
8. Diarrhea
![Top 10 Most Lethal Diseases - Diarrhea](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_uDha3quZ7sY-eKY8YbLfxitpAKotvM1mae9TQk0iB9WWveCE2MStYJxummfVSW5DF8W7gHmjLanaU8ZhK4eComd_vrYk9_S3ojRkclscnhb8j3QwV_pzijYWnxShAfTwV2jTU7y_bsAVLzQ8tPKTc37NfDdalkq3KoGnWTgdQVNHyxYw=s0-d)
The increase in frequency of intestines movement or the increase in
the looseness of stool or both is known as diarrhea, gastroenteritis is
its most common cause. It is characterized as one of the most noxious
diseases in the third world countries. It can be either acute or chronic
with different causes and treatments. Acute diarrhea has rapid onset,
lasts for few days and is not long term is a most prevalent cause of
death among young children and babies in developing countries. Chronic
diarrhea that is referred as long term diarrhea is the second cause of
death of children in developing nations. The complications of diarrhea
include dehydration, electrolyte imbalance and anus irritation. The
dehydration should be immediately treated with oral intake or by with
intravenous fluids and further treatment of disease with medication.
Diarrhea is the second most common cause of death of infants in all over
the world, killing almost 2,195 children everyday that is more than
malaria, measles and AIDS combine.
7. Tetanus
Tetanus is a disease that is caused by the bacterium Clostridium
tetani as its spores are widespread in our environment. The neurotoxin
produced by this bacterium in the absence of oxygen is responsible for
the effects. The contaminated wound is the source of disease and can be
prevented by proper vaccination. Tetanus is also known as locked jaws
and therefore characterized by muscles spasms, initially in the muscles
of jaw. With the progression in the disease the mild stimuli may provoke
generalized seizures like activity. Its major complications include
laryngospasm, fractures of bones and ultimately death unless supportive
treatment is given. It is a medical emergency that immediate require
hospitalization and immediate treatment with tetanus immune globulin,
tetanus vaccine, antibiotics, wound management and dugs to control
muscle spasm. Depending on the severity of disease the ventilator is
also required for breathing.
6. Anthrax
It is an acute and life threatening infectious disease that is caused
by bacterium Bacillus anthracis. It can affect both animals and humans,
as human get infected by in contact with animals that are infected or
their products. Anthrax terrorist attack has caused this disease to
receive a great deal of attention. There are three types of anthrax;
cutaneous anthrax, gastrointestinal anthrax and inhalation or pulmonary
anthrax.
The inhalation of spores of this bacterium causes the most deadly
type of anthrax. Its sign and symptoms vary according to the type of
disease as boil or swelling of lymph nodes in case of cutaneous anthrax,
nausea, vomiting, fever and bloody diarrhea in case of gastrointestinal
anthrax whereas flu like symptoms and chest discomfort in case of
pulmonary anthrax.With the progression of disease it causes fever,
difficulty in breathing, meningitis and shock, its most fatal
complication is hemorrhagic meningitis. Powerful antibiotics are
available that aid in treating this disease, this disease can also
prevented by vaccination and avoiding contact with affected animals and
early detection and treatment is very important. If you are not taking
treatment within 24 hours of inhalation then it is going to kill you by
the third or fourth day.
5. Dengue Hemorrhagic Fever
Dengue Hemorrhagic Fever also termed as dengue vasculopathy is a
severe and possibly lethal infectious disease that is caused by the
species Aedes aegypti of mosquitoes. It is a life threatening condition
in which the early symptoms are like dengue fever like fever, vomiting,
headache, malaise, decreased appetite and joints or muscles aches but
with the passage of time there are symptoms of bleeding, blood plasma
leakage and low levels of platelets of blood or due to extremely low
blood pressure the patient can go into dengue shock syndrome and that
can lead to the death of the individual.
There is no specific treatment of this disease as it is caused by a
virus so there is no known vaccine or cure, the only possible treatment
is to treat the symptoms. With early diagnosis and intensive care, most
of the patients show good prognosis whereas almost half of the untreated
patients go into shock and do not survive. Approximately 50- 100
million people are infected from this disease, annually. Now a days,
most of the Asian and Latin American countries are affected by this
disease and therefore becoming a leading cause of hospitalization and
death in that regions.
4. Ischemic Heart Disease
The most common cause of death in most of the Western countries is
Ischemic Heart Disease. Heart is the pumping organ of the body, any
malfunction in its activity can be extremely hazardous. In ischemic
heart disease also known as coronary heart disease there is decreased
blood supply to heart because of narrowing or blockage of the blood
vessels due to plaque formation, therefore leading to death of the
tissue and causing heart attack.
Ischemic heart disease is the commonest type of heart diseases and
therefore a commonest cause of heart attack that cause sudden death too.
Its sign and symptoms include acute chest pain and in case of heart
attack difficulty in breathing and swelling of extremities due to
weakened heart muscles. Smoking, diabetes, high cholesterol levels and
hypertension are major risk factors for this disease. Its treatment
includes improved life style, medication and surgery. Healthy life style
plays a basic role in preventing this disease, regular exercise,
healthy diet, avoid smoking and decreased obesity are leading factors in
avoiding this disease. This disease affects individuals of any age but
is more common in older age. It is a leading cause of death world widely
as according to 2008 estimation it caused 7.3 million deaths and it
causes approximately 600,000 deaths in the United Sates annually.
3. Cerebral Malaria
Malaria is one of the greatest killers in the world that causes
almost one million deaths annually and its most serious and deadly form
is cerebral malaria that affects the brain and damages it. The children
are more prone to this lethal disease as compared to adults. It is
constituted of the clinical manifestations of malaria caused by
plasmodium falciparum and causes alterations in mental status and even
coma. It is an intense form of brain disease that form ring like lesions
in brain along with fever. The symptoms include altered consciousness
with fever, neurological abnormalities and convulsions, and coma that
persist for 24-72 hours.
If not treated on time it gets fatal and can lead to many other
severe complications and death. It can be prevented by anti malarial
chemotherapy and additional measures. According to World Health
Organization nearly 300-500 million are become victim of this disease
and causes more than one million deaths therefore its mortality ratio is
very high as compare to other forms of malaria.
2. AIDS
Acquired Immunodeficiency disease is a very dangerous disease and is
caused by HIV virus also known as human immunodeficiency virus. It is a
disease of the weakening of the immune system of the body making the
individual more vulnerable to diseases and infections including
opportunistic infections and tumors and with the progression of disease
the condition becomes more worsen.
This virus is transmitted by sexual intercourse, pregnancy and
through blood transmission by sharing and reusing contaminated syringes.
There is no treatment or vaccination of this disease
but antiretroviral vaccination helps slowing down the disease’s course
and reduces the risk of death but is expensive and has various side
effects. It is considered a pandemic as it is widely spreading and is
present over a large area in this world. The main causes of death from
this disease are opportunist infections and tumors due to weakened
immune system. As of 2012 epidemiology, approximately 35.3 million
people were suffering from this disease world widely with 2.3 million
new cases in that year and caused death of about 1.6 million people that
is reduced as compared to 2.2 million in 2005.
1. Lung Cancer
Cancer itself is a very lethal disease but Lung Cancer
is its most lethal type. It is the leading cause of deaths by cancers
not only in the United States but also in all over the world. It is
defined as a disease in which there is uncontrolled division of cells in
lung tissues and if left undiagnosed or untreated this unwanted and
uncontrolled division can metastasize to nearby tissues or other body
parts. Cigarette smoking is the most common cause of this disease, while
the other causes include passive smoking, exposure to asbestos, radon
gas, air pollution or a combination of genetic factors.
The most common symptoms of this disease are cough, blood in cough,
shortness of breath and weight loss. Its treatment methods include
chemotherapy, radiotherapy and surgery or a combination of medical aids.
Only 15 percent of lung cancer patients survive more than five years
and causes approximately three millions deaths annually and around
35,000 people are died because of this lethal disease in United Kingdom
each year.